BXRX
BXRX: Computational cancer drug combination prediction and validation
BxRx is a computational cancer drug combination prediction and validation solution in 3D cell models of patient tumors.
BxRX works as a platform-as-a-service that will support the work of clinical development in Pharma & Biotech companies.
The solution is based on a computational evidence-based network medicine platform for improving success in drug development by providing deeper insights and accelerating the process of finding the right indication & patient for the right drugs through big data analytics and AI, by using Natural Language Processing, Machine Learning, and Graph Analytics algorithms together with public/private medical records, clinical trials, (bio)medical literature, and genomics data.
This data will then be validated in cancer patient-derived tumor biopsy models that can be cultured in 3D, mimicking the actual tumor micro-environment, to test if the treatment works, before it’s given to the patient.
BXRX’s expectations from the acceleration programme:
- Validated and market ready product targeting Pharma market.
DigiCirc financial support: €117,500
The financial support was used for advancements in the prototype, perform tests and prepare marketing materials.
Entities
Country
IrelandCountry
PolandMeet the team
Agnieszka Pietrzyk
Is a Real Research-ian working on a biotechnologist position in Real Research for the last two years. She graduated from a biotechnology department at the Jagiellonian University in Kraków. Agnieszka is also a passionate programmer and finished HelloAI RIS Online; Back-end Developer: Python; and now starts Data Science in Python.
Pavels Kartasevs
Pavels has a dual Master degrees, both completed with distinction (top of the class): Engineering degree in Computer Science and MSc in Bioinformatics. His last Master’s thesis was in Biological patterns (electronic nose) data classification and recognition machine learning approaches using GPGPU (predictive modelling project). He also has a MEng in Computer Science and Computer Control.
Marcin Krzykawski
Is a co-founder and CEO of Real Research. Marcin has done his PhD in medical sciences and worked on novel anti-cancer therapies. He is one of the inventors of the LifeGel technology and an experienced scientist. He attended multiple business training programs like Kauffman Foundation entrepreneurial program and Ignite from Judge Business School.
Anna O’ Leary
Ceo & Co-founder at BioXplor