INSILICO
INSILICO: a bio-platform for true plastics circularity
NSILICO works on engineered enzymes to safely turn plastic waste into raw materials for new high-quality plastic – with lower resource requirements and emissions, at competitive prices.
INSILICO’s engineered enzymes safely turn plastic waste, including plastic-containing mixed and otherwise difficult-to-handle waste streams, into inputs for new virgin-grade plastic – a true plastics circularity.
INSILICO uses genetically modified microbes to produce custom active proteins (enzymes) that work to depolymerize plastic into its constituent components, which can be retrieved and used for producing new high-quality plastic.
Using specialized enzymes ensures that the process is highly selective (which means less pre-processing for plastic waste), runs at lower temperatures (which means lower energy demands), and results in ~40% less CO2 emissions. The fact that the outputs are plastics precursors means that there’s no degradation in quality over the entire cycle, opening the doors for a potentially infinitely looped plastics economy.
INSILICO works as a “pluggable” process into the existing plastics value chains.
INSILICO’s expectations from the acceleration programme:
- Structure, know-how and networking to bring the technology to demo-readiness
- Develop the business plan and iterate on the technology
DigiCirc financial support: €117,500
The grant has provided additional runway and more opportunities to extend both technology development (e.g. consumables and equipment) and market validation (e.g. industry events).

Meet the team
Andrii Shekhirev
MSc Management and Finance; coordination, business development
Aleksejs Kolpakovs
MSc Innovation Management; cross-functional leadership, finance
Alise Pizika
MBA. BA Public Relations sustainability and circular strategy
Inga Berkovica
MSc Human Decision Science; marketing and communications
Janis Liepins
PhD Microbiology and Biotechnology; microbial growth and metabolism
Elina Dace
PhD Environmental Engineering; plastics circularity














